Did you try last release 82fd8ae ?
I have try with Win10 64/32 bit and on my netbook it works perfectly, from 50 ms (and less) to 200 ms (and more).
For Win10, like in SimpleDrums demo, a endless-muted input is needed. This because Win10 has a (strange) way to work: when the audio drivers does not receive any samples, it is set in "sleep" mode.
And this make synchro not working (it takes time to wake-up the driver).
The solution is to associate a endless input so the audio driver is not set in "sleep" mode when the wave-file has terminated.
@ other uos users: is the demo SimpleDrums working for you ?